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"Hold-up", the documentary on Covid-19 confronted with scientific facts

In the film "Hold Up - retour sur un chaos", Pierre Barnerias and Christophe Cossé claim to be trying to answer questions about the coronavirus. The reality is more complicated.

SCIENCE - It's what you might call a runaway success. Released on Wednesday 11 November, the documentary devoted to Covid-19 "Hold Up - a look back at chaos" is at the heart of discussions in many media and on social networks.

On the Tipeee crowdfunding platform, the Tprod production company went from receiving 28,000 euros in monthly funding to over 110,000 euros in 24 hours, as noted by Tristan Mendès-France, a researcher specialising in digital technology and conspiracy circles. The various extracts from the film posted on social networks have accumulated hundreds of thousands of views. And given the sums already amassed, the target of 200,000 euros a month to make the film available free of charge could well be quickly reached.

But what exactly does this documentary, which has been accused of peddling a conspiracy message, say? Le HuffPost has watched it in its entirety, and below we take a look at some of the false information spread by "Hold-Up" on the coronavirus and management of this global pandemic. This article will be updated regularly.

The Great Reset

Before going into detail, we need to return to the main thesis of this documentary, which takes two hours to appear on screen. According to "Hold-Up", this pandemic was organised by political, economic, intellectual and technological elites to bring about a "Great Reset" of society.

The World Economic Forum is planning to hold a major meeting in January 2021. This was announced in a press release in June. The aim of this project is to devise an "economic and social system for a fairer, more sustainable and more resilient future" in the face of pandemics, climate change and other challenges.

While it is perfectly legitimate to debate the true usefulness of the World Economic Forum and this meeting, to assert that this "Great Reset" has been in the works for a long time is factually inconsistent. The documentary presents no evidence to support this claim.

Still without proof, the authors claim that the purpose of this pandemic for the global elites is both to destroy a useless part of humanity, but also to facilitate the deployment of 5G to better control money, via the virtualisation of money through cryptocurrencies.

It may sound like a big deal when you put it like that. But after two hours of debate on the origins of the coronavirusWhen we look at the real impact of Covid-19, mortality, treatments and the ethics of confinement, we are legitimately keen to hear a solution that explains all this.

Except that the overwhelming majority of what we've heard before is also either false, exaggerated or misleading. Here are a few examples. Many are conspiracy theories or approximations that have been around for months.

The efficacy of hydroxychloroquine 

It's one of the subjects that has led to the most debate and polarisation, not only on social networks, but also among doctors and politicians. So it's only logical that Hold Up should take up the subject.

There are many claims to be made on this subject, and it would be futile to try and review them all. It is clear, however, that the documentary asserts that hydroxychloroquine is a highly effective treatment for Covid-19. Hold Up also states that the reason this drug was not authorised was precisely because there was a large-scale conspiracy to ensure that the drug was not authorised. coronavirus cannot be treated until a vaccine arrives.

After several months of debate, there are some clear points to be made about chloroquine. Firstly, it should be remembered that in the early months of the pandemic, we didn't know what to do about the disease. coronavirus. It therefore makes sense to test existing drugs, such as chloroquine and Remdesivir (which is heavily criticised in Hold Up because it comes from the Gilead laboratory, which is supposed to be part of a grand conspiracy).

Some drugs seemed to be effective, but the results were only partial. One of these was hydroxychloroquine, which Didier Raoult was promoting at the time. The question of whether doctors should be allowed to prescribe is a debate in its own right (more information here). However, it is clear that the media coverage of this debate, particularly as a result of the statements made by the professor from the Marseille IHU and by Donald TrumpThese controversies, which are commonplace in the medical world, have not been helped. And they have had undesirable effects.

But things have moved on since then. Behind these ethical debates, there is scientific research that has tried to move forward quickly (more details here), to produce high-quality, robust studies that can tell us with much greater certainty whether the existing drugs tested in the emergency were of any use against Covid-19.

Hold Up also talks a lot about the famous study published in The Lancetwhich led the WHO to suspend (and then resume) its analysis of the efficacy of hydroxychloroquine. And rightly so. These problems were raised by scientists and the media (summarised here). The study was retracted by the scientific journal and research continued to progress. On the other hand, Hold Up does not mention the many approximations and untruths expressed by Didier Raoult in his various interviews or in some of his studies.

The fact remains that today, after all the debate and controversy, we know a lot more about Covid-19. Dexamethasone is one of the only drugs with truly proven efficacy in well-controlled double-blind clinical trials, and no-one had really bet on it. Conversely, a large number of clinical trials have concluded that chloroquine is effective. The two largest of these, from the WHO (solidarity) and Oxford University (recovery), all agree that hydroxychloroquine has no effect.

Researchers also carried out a meta-analysis and found no impact. This study is heavily criticised in Hold Up, but the majority of other similar analyses point in the same direction.

The mask for non-patients is an "aberration".

Pascal Trotta, a nutritionist and anti-vaccine doctor, states in "Hold-Up" that "doctors who put masks on people who aren't ill are fools, Molière's doctors".

The usefulness of the mask was debated at length at the start of the epidemic, as we have explained several times. And not to mention the mistakes made by the various governments, even the scientists disagreed. But after more than 11 months, there are some things we know that constitute a scientific consensus. This consensus is created by the accumulation of studies, tests, analyses and observations.

This is very clear: it is possible for a person infected with coronavirus transmit the disease without showing any symptoms. Particularly in the 48 hours before symptoms appear. It is also increasingly clear that masks reduce the risk of contamination.

Logically, if the coronavirus circulates widely in a population, asking people to wear a mask should reduce the proportion of pre-symptomatic or asymptomatic people who will contaminate healthy people.

There has been a bonus for doctors who "blow the whistle".

The documentary claims that doctors were rewarded for reporting Covid-19 cases and their contacts. It is true that the issue was the subject of debate in May, when the government was putting in place its decontainment strategy, based in particular on contact tracing.

But as LiberationHowever, when the law was finalised by the joint parliamentary committee, the issue of remuneration for this tracing work was dropped. On the other hand, it is true that for a sick patient whose PCR test confirms that he or she is indeed affected by the coronavirusthe doctor gets a bonus.

Why should I do this? Health insurance explained to LiberationThis increase corresponds to the value of the announcement of the positive test, the prescription of tests for close contact cases [...], the information given to the patient on barrier measures, and the registration of the patient and close contact cases in the "Contact Covid" tool".

The WHO has banned autopsies on Covid-19 victims

In "Hold-Up", we hear a doctor explain that autopsies are useful for finding out how best to treat Covid-19 patients. Just before this, the documentary states that the WHO had in fact banned autopsies.

However, a visit to the World Health Organisation's website shows that this is not the case. A document published on 24 March lists the precautions to be taken during an autopsy on a patient who has died of Covid-19 in order to avoid possible infection. This AFP article provides a detailed update on this issue.

The virus was created in a laboratory

It's one of the theories that has circulated the most on social networks. And in many different forms. In "Hold-Up", while some contributors explain that they do not have the answer to the origins of Sars-Cov2, others are more categorical. Like Jean-Baptiste Fourtillan, an anti-vaccine campaigner known for having taken part in a wild clinical trial in an abbey, who claims that the new coronavirus is a Sras genetically modified with bits of the malaria genome. The proof is in the patents.

The origin of Sars-Cov2 is still unclear, but this hypothesis of genetic modification is rejected by the scientific community, especially as these patents do not at all mean that the virus was "created" years earlier, as we explained in March.

The genome of the coronavirusThe Sars-Cov2, which has been studied in detail for 11 months, does not seem to support the theory that it was modified by humans, for a number of reasons (more details here). In particular, this theory gained momentum after an investigation by the US intelligence services in April, which finally concluded that Sars-Cov2 was not man-made.

The scientific community still does not know exactly how it reached humans. An intermediate host, such as the pangolin, could have been the link between the bat and man, but the debate remains open.

A law on containment from 2019

After an hour and a half, "Hold-Up" slowly begins to lead the viewer down the path of a long-planned plot, a way of preparing the ground for the thesis of a "Great Reset" fomented in the shadows. The documentary then refers to a French law that would have made "confinement legal"... from December 2019.

When questioned, MP Martine Wonner, who was expelled from the LREM group for her (sometimes questionable) positions on the coronavirus, wondered: "It's very surprising, I admit to you that it's practically been passed over in silence", explaining that "we can ask ourselves the question".

The text in question is not specified, but on the Senate website there is a "health security bill" dated 5 December 2019. It refers to "eviction and home maintenance measures" for "persons presenting a high risk of developing a transmissible disease". Another article in the proposal refers to compulsory isolation measures "when a person suffering from a highly contagious transmissible disease creates a serious risk to public health by refusing to comply with medical prescriptions for prophylactic isolation".

But you only have to look at the explanatory memorandum to this law to put all this into context and understand that there were reasons prior to Covid-19 to justify this law. "Our country is facing growing difficulties in the face of the development of vector-borne diseases transmitted by insects, such as dengue fever, chikungunya, zika and yellow fever", says Senator Michel Amiel. A few months earlier, the Zika virus was contracted for the first time in mainland France.

The senator also mentions the return of measles, which highlights "that the State does not have all the necessary means of action". In 2019, France is being singled out along with other countries for the return of this disease, which was thought to have been brought under control. The fact that the French population is one of the most opposed to vaccines is no coincidence.

By Grégory Rozières Head of the C'est Demain, Science and Technology section

COVID-19: Pfizer announces that its vaccine is "effective at 90%".

This "vaccine efficacy" was measured by comparing the number of participants infected with the new coronavirus in the group that received the vaccine and the placebo group.

Pharmaceutical giant Pfizer said on Monday that preliminary data showed that 90 % of its COVID-19 vaccine was effective, which could enable it to apply to the US authorities for emergency authorisation for its use later this month.

Monday's announcement does not, however, mean that a vaccine is imminent: this interim analysis, carried out by independent experts, examined the 94 infections recorded so far among the 44,000 or so people taking part in the study in the United States and five other countries.

Pfizer did not provide further details about these infections and warned that the initial rate of protection could change by the end of the study. Even the disclosure of such preliminary data is unusual.

"We are able to potentially offer some hope," Pfizer's vice president of clinical development, Dr Bill Gruber, told the Associated Press. We're very encouraged."

The markets reacted favourably to this announcement. Bonds of around 5 % were rated on Monday morning, both in Europe and the United States.

Officials repeat that it is highly unlikely that a vaccine will be available before the end of the year. And when a vaccine is offered, the quantities initially available will be carefully distributed.

The vaccine developed by Pfizer and its German partner BioNTech is one of ten candidates currently in advanced clinical trials around the world. Another pharmaceutical company, Moderna, also hopes to be in a position to request emergency authorisation from the powerful US Food and Drug Administration later this month.

The participants in the clinical trials, and the researchers, do not know who received a vaccine and who received a placebo. But a week after the second dose, Pfizer began counting the number of subjects who had symptoms of COVID-19 and in whom the coronavirus had been detected.

As the study is ongoing, Dr Gruber was unable to say how many participants in each group were infected. However, a quick calculation reveals that virtually all the infections occurred among the subjects who had received the placebo.

Pfizer will continue the study until 164 infections have been detected among participants, a figure the FDA considers sufficient to measure the vaccine's efficacy. The US agency has indicated that an efficacy rate of at least 50 % will be required.

No subjects were seriously ill, said Dr Gruber. Nor could he specify how many infections occurred in older subjects, for whom COVID-19 can be particularly dangerous.

Only symptomatic participants were tested, so it is not known whether vaccinated subjects could have been infected and continued to spread the virus without knowing it.

With the pandemic still raging, pharmaceutical companies are hoping to ask the world's governments to authorise emergency use of their vaccines while testing continues. This would enable them to get their products to market more quickly, but would also leave certain scientific data concerning their products in abeyance.

By quebec.huffingtonpost.ca

Donald Trump has 75 days left of his presidency: what if they were the worst?

Although defeated by Joe Biden, the future leader of the United States, the incumbent retains immense power as President and head of the armed forces... and he has nothing to lose.

UNITED STATES - As Donald Trump prepares to enter the final days of his presidency - which could well be his worst - Americans are worried about what is in store for a president who proposed shooting migrants and using nuclear weapons against hurricanes.

As excessive, reckless and thoughtless as he has been so far, his critics point out that it was election time, which is no longer the case. Beaten by Joe Biden in the 2020 presidential election, he no longer needs to moderate himself.

"He'll do everything he can to stir up trouble", says Michael Cohen, the president's former personal lawyer, who was tried and sentenced to three years in prison for, among other things, buying the silence of women who had relations with Donald Trump just before the 2016 election.

According to him, the President "will go on TV, radio and the press to complain that these elections were stolen from him by fraud and foreign interference. He will never admit that he owes his defeat to his incompetence and arrogance".

Trump to leave the White House on 20 January

The winner, Joe Biden, is due to take office at noon on 20 January 2021, but Donald Trump retains his presidential prerogatives for another 75 days, including his role as head of the US armed forces and nuclear weapons.

He said he had no intention of facilitating the transition of power because of the FBI investigation into Russian assistance he allegedly received during the 2016 campaign, which the president calls "espionage."

"Are we talking about the transition I had when you spied on my campaign and when you tried to bring down the President of the United States?" he railed again last week at a rally in Pennsylvania.

The White House declined all requests for comment on this matter.

Speaking on condition of anonymity, a former senior official believes that the concerns expressed by Michael Cohen and others are exaggerated. "I don't think he'll do anything out of the ordinary", he said of the President.

But a long-standing adviser, who also prefers to remain anonymous, fully expects Donald Trump to demand the resignation of Anthony Fauci, the infectious disease specialist on the coronavirus pandemic task force. He could also fire Christopher Wray, the director of the FBI, and Gina Haspel, the director of the CIA, who have repeatedly contradicted him. "Either he's going to fire Wray, Fauci and Haspel and make a fuss, or he's going to hold his nose to make himself look good. It'll be interesting to see. And it's 50-50," he adds.

What if Trump spent all his time playing golf?

Ruth Ben-Ghiat, a historian and specialist in authoritarian regimes at New York University, is sure that the outgoing president "will take revenge on those who have shown him a lack of loyalty". Daniel Goldman, a former federal prosecutor who acted as the Democrats' lawyer in the impeachment proceedings against Donald Trump, predicts 11 busy weeks for the President and his team.

According to him, we can expect "all sorts of executive orders to invalidate other Obama-era regulations, the adoption of new regulations on the sly, attempts to intimidate and neutralise various government agencies, and him using the levers of power to advance the pawns that will serve his financial interests after the presidency. Not to mention a record number of presidential pardons" for his accomplices.

Of course, regulations that have been improperly drafted and adopted can always be invalidated by legal action. Even those that are properly drafted in the final months of the administration could be quickly repealed by the new Congress, and all its executive orders immediately rescinded by Joe Biden as soon as he takes office.

Other people familiar with Donald Trump question the interest he will show in his duties if he loses the election. Anthony Scaramucci, an old friend of the president who briefly served as a White House adviser, sums up the leader's most likely end-of-term agenda in three words: "Play golf". Which is what he was doing when his defeat was announced to the world.

This article, published on Le HuffPost USwas translated by Valeriya Macogon for Fast ForWord.